How are you dosing IVIG following BCMA CAR-T or bispecific antibodies in multiple myeloma?

Topics: Medical Oncology • Myeloma • NCI-CCC Tumor Board Question • University of Washington • NCI-CCC Myeloma Tumor Board Question • Multiple Myeloma

Do you only offer it for patients with a documented IgG < 400? Do you check the IgG at all, or are you doing primary prophylaxis?

Answer from: Medical Oncologist at Community Practice

At our institution, primary prophylaxis is the rule because we forget. All patients on a bispecific get IVIG 0.4 g/kg (ideal body weight) starting day 1 of the second month and this continues while they remain on the BsAb. Each physician/APC team can stop the IVIG if the IgG > 500 and is s...

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Medical Oncologist at University of Washington, Fred Hutchinson Cancer Research Center
Agreed with this answer x1000 - especially because...

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