How are you dosing IVIG following BCMA CAR-T or bispecific antibodies in multiple myeloma?

Do you only offer it for patients with a documented IgG < 400? Do you check the IgG at all, or are you doing primary prophylaxis?

1 Answer

Mednet MemberInvited Expert

Medical Oncology · Winship Cancer Institute of Emory University

Answered on

At our institution, primary prophylaxis is the rule because we forget.

All patients on a bispecific get IVIG 0.4 g/kg (ideal body weight) starting day 1 of the second month and this continues while they remain on the BsAb. Each physician/APC team can stop the IVIG if the IgG > 500 and is self-susta...

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