Has your practice changed to PLEX-free initial therapy for iTTP?

I am not. The reason is that caplacizumab is not on formulary at my institution, and so implementing PLEX rapidly while obtaining caplacizumab (which typically arrives in 24-48 hours) is my current practice.

If I had caplacizumab on formulary, I would utilize it as it was utilized in the MAYARI tria...