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How are you sequencing immunotherapy with zolbetuximab in locally advanced/metastatic GEJ cancer when CPS >5 and Claudin 18.2+ (>75%)?

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Mednet Member
Mednet Member
Medical Oncology · Mayo Clinic

In Claudin+:
CPS 5 and above, would do checkpoint+ chemo

CPS less than 5, would do chemo +zolbe.

There is an ongoing study that will answer the question of the quadrable therapy. Till then, would do as the above given that CPI can give us OS benefit, and also ORR benefit, which was not very impressi...

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