How are you thinking about incorporating mirtazapine into your treatment approach for patients with methamphetamine use disorder?

In my experience as an addiction psychiatrist in Maryland, I always found mirtazapine to be a low-hanging fruit in my "dual diagnosis" patients, re: reasonably quickly helping with insomnia and poor appetite that comes with drug use or especially opioid withdrawal. Also comes with the potential plus...

This answer was co-written by Professor Rebecca McKetin, BSc (Psychol) Hons, PhD.

Prescribing would be off-label, as there are no regulatory-approved medications for methamphetamine use. This would mean following local guidelines on off-label prescribing, reviewing evidence for mirtazapine (3 clinic...