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Topics:
Hematologic Malignancies
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Medical Oncology
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Myelodysplastic Syndromes
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Hematology
How do you approach a patient with CMML requiring platelet transfusions?
Would you consider use of TPO-R agonists such as eltrombopag or romiplostim for a patient like this?
Related Questions
Are you now using luspatercept as your first choice for anemia management in patients with low-risk MDS otherwise appropriate for EPO initiation, regardless of presence of SF3B1 or ringed sideroblasts?
Is there an advantage to early therapy with hypomethylating agents for high/very high risk patients with MDS who are not transplant candidates and have only mild cytopenias?
What are common indications for ordering NGS of peripheral blood?
Would you still recommend bone marrow biopsy in an elderly non-transplant eligible patient with mild cytopenias if NGS from peripheral blood indicates MDS mutations?
How do you treat an MDS patient who presents with significant cytopenias who is not a candidate for lenalidomide or luspatercept? How do you initiate an HMA when they are severely neutropenic?
What hemoglobin level prompts you to start erythropoietin in a patient with low-risk MDS?
Do you use lenalidomide for patients with MDS with 5q- without other cytogenetic abnormalities but with one or more mutations on NGS?
How do you utilize immunoglobulin testing to affect treatment decisions in patients with myeloma?
How would you approach the treatment of an elderly patient with multiple myeloma and CALR+ myelofibrosis with elevated platelets?
Would concurrent CRLF2/IgH rearrangement affect your treatment recommendations for an adult patient with Ph+ p190 high risk (Age>35, WBC >30) B-cell ALL that was started on induction therapy with ponatinib + blinatumomab?