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How do you approach adjuvant chemotherapy for high risk/advanced endometrial cancer patients?

Does your approach to the number of cycles vary based on plan to include radiation therapy or presence of certain histopathologic features?
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Mednet Member
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Gynecologic Oncology · Center of Hope
Answered on

For patients with high risk/advanced endometrial cancer where adjuvant therapy is advised, I recommend paclitaxel (175 mg/m2) + carboplatin (AUC 6) (TC) every 3 weeks for 6 cycles. Data from GOG #209 strongly support this recommendation. In this large prospective study, TC demonstrated noninferiorit...

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