How do you approach ADT in a post-prostatectomy patient who had higher Gleason score on biopsy but a lower Gleason score on final pathology?

Topics: Radiation Oncology • Genitourinary Cancers

For example, if patient had Gleason 4+5 on biopsy but Gleason 4+3 with Tertiary Grade 5 on final pathology? Would you consider intensifying their hormone therapy with longer duration or addition of Abiraterone?

Answer from: Radiation Oncologist at Academic Institution

I would only base my decision on the pathology of the final prostatectomy specimen, and ignore the prior biopsies.

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