How do you approach an otherwise healthy patient with an incidental 1 mm GIST involving the serosal surface in terms of staging workup, EGD, and surveillance?

We will need more information like location and mitoses per 50 HPF (or 5 mm). Please use the Sloan Kettering nomogram to determine the risk of relapse. Seems like a very low risk of relapse. NCCN recommends 6-month scans for the first 2 years and then once a year to finish 5 years. There is no need ...

These incidental "micro-GISTs" are not likely to become a clinical problem. Interestingly, you describe a "serosal" lesion which would not get picked up on endoscopy anyway, but not unreasonable to check again in a year with a CT AP and EGD. I don't think we have any evidence to support continued lo...