How do you approach an otherwise healthy patient with an incidental 1 mm GIST involving the serosal surface in terms of staging workup, EGD, and surveillance?

An EGD periodically, driven by the reason why the patient needed it in the first place, could guide the interval. I would not subject the patient to CT scans or routine oncology follow-ups.

We will need more information like location and mitoses per 50 HPF (or 5 mm). Please use the Sloan Kettering nomogram to determine the risk of relapse. Seems like a very low risk of relapse. NCCN recommends 6-month scans for the first 2 years and then once a year to finish 5 years. There is no need ...