Please select the option that best describes you:
Topics:
Psychiatry • Consultation-Liaison Psychiatry • Geriatric Psychiatry • Depression • Major Depressive Disorder
How do you approach antidepressant selection in patients with prolonged QTc?
Is there a QTc threshold at which you avoid specific agents? Which antidepressants do you prefer or avoid? Do you routinely involve cardiology? How do you counsel patients about risk?
Answer from: at Community Practice
Based on a large-scale review (Pillinger et al, Lancet 406:2063, 2025), the only antidepressants which tended (not statistically significant) to increase QT interval in the general population of depressed patients were doxepine, nortriptyline and amitriptyline.
Sign In or Register to read more