Topics:
Hematologic Malignancies • Pediatric Oncology • Medical Oncology • Bone Marrow Transplant • Hematology
How do you approach autologous stem cell transplant in T-cell lymphomas/PTCL after induction chemotherapy with achievement of CR1?
NCCN says "consider autologous HCT" while retrospective data seems to support SCT in most histologies like AITL
Answer from: at Community Practice
Autologous SCT can be considered in PTCL in CR1 especially if the patient is MRD negative by PET and molecular testing (by checking for the persistence of clonal T cells, for example). Schmitz et al., PMID 33512419 If MRD positive CR or PR/SD, would consider allogeneic SCT instead. The main con...
Sign in or Register to read more