How do you approach chemotherapy use in patients with locally advanced ER+/HER2 negative patients with cirrhosis and platelets < 100K?

For instance, in stage III, would you use chemotherapy in neoadjuvant or adjuvant setting? What regimen would you use?

1 Answer

Mednet Member

Medical Oncology · Ohio State University

Answered on

This is fortunately a rare situation encountered in breast cancer patients but in those situations it poses a challenging problem. In general, I look at this as two categories: In patients with compensated cirrhosis (with Child-Pugh score less than 7 and no clinically detectable ascites), the mortal...

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