How do you approach delivery planning in patients with T1 vWD?

For VWD, I recommend that the mode and timing of delivery be obstetric-based (i.e., the presence of VWD has no effect on the decision). If a CSX is needed, I consider an epidural safe if preceded by VWD-specific therapy. I base the duration of VWD-specific therapy on clinical history and 3rd-trimest...

I agree with Dr. @Dr. First Last comments. Also, while it's a conditional recommendation per the 2021 VWD guidelines (Connell et al., PMID 33570647), we usually offer TXA 1.3 g po tid for 10-14 d as there is a sizable risk of secondary PPH as VWF levels start to fall as early as 3 days (per Royal Fr...