How do you approach discussing the pill burden of voclosporin with patients who already have to take a regimen such as MMF+HCQ+ACEi and possibly more?

Medication adherence and a chronic disease such as lupus is an issue regardless of the number of medications. For example, hydroxychloroquine is very effective, but studies often show poor adherence as measured blood levels may be undetectable or below the intended therapeutic target.

For patients wi...

I educate them on how important it is to do everything we can to achieve complete remission ASAP in order to prevent end-stage kidney disease. Taking a lot of pills now, followed by a high chance of taking just a few pills in a few years of remission, is worth it compared to going into kidney failur...