How do you approach evaluation and management of arthralgia in a patient after CAR-T cell therapy?

This is a great question - part of cytokine release at syndrome includes joint pain. So my questions are:

1. How far after?
2. What was the reason for the CAR-T?

These are vital questions to understand first. To that be said - the answers will determine if you give a one-and-done treatment or long-term....