How do you approach HCC screening in patients with advanced fibrosis e.g., F3 on FibroScan?

We should first understand the underlying principles that defined the various cut-offs that resulted in this recommendation (eg, cost-effectiveness threshold for HCC screening, cut-offs for advanced fibrosis) and then go from there.

• Among patients with cirrhosis, the cost-effectiveness threshold was determined to be an ultrasound screening every 6 months in individuals with an annual HCC risk of 1.5% who would be able to tolerate liver cancer treatments if HCC were found. Therefore, don't need ...