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Pulmonology • Lung Transplant
How do you approach induction immunosuppression in patients with high PRA undergoing lung transplantation?
Answer from: at Academic Institution
At my institution, if PRA >30%, we perform preoperative plasma exchange and administer preop eculizumab along with our standard preop basiliximab and methylprednisolone. If the crossmatch is positive, we subsequently perform daily plasma exchange followed by eculizumab for the next four days. The...
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Answer from: at Academic Institution
We do not modify induction IS based on PRA. All patients get basiliximab 20 mg on Day 0 and Day 4.
We list unacceptable antigens based on the MFI values determined in our clinical immunology&nbs...