New: NCI-funded clinical trial search
Mednet Logo

How do you approach management of GLP-1 receptor agonist therapy in patients who develop NAION?

Community PollStarted

Do you discuss risk of NAION with patients on GLP-1 agonists?

66 physicians have voted

Join Mednetto vote and see how they answered.

2 Answers
Mednet MemberInvited Expert
Ophthalmology · George Washington University School of Medicine and Health Sciences
Answered on

Short answer is I recommend stopping the GLP-1 agonist if one eye has already developed NAION, for the sake of protecting the fellow eye.

The fact is, our knowledge is still growing in this matter. While some studies indicate links between GLP-1 agonists and NAION, there are so many discussions around that. AAO and NANOS have provided some guidance on this. I think if a patient develops NAION in one eye, as there is a 20-30% chance for involvement of the other eye, every effort is valuable to re...

Join for free or sign in to see the full answer

Mednet Member
Ophthalmology · Ophthalmology Associates Of The Valley
Answered on

Great discussion. I think we are still far from a clear understanding of this topic. Much larger prospective studies are needed to provide more accurate guidance.

Join for free or sign in to see the full answer