How do you approach patients for definitive chemoradiation in locally advanced NSCLC who have severe neuropathy?
Are the other options of chemotherapy that can be used instead of platinum based doublets, including with paclitaxel?
Answer from: Medical Oncologist at Academic Institution
If the patient and treating physician are willing to take a calculated risk for a curative intent CRT, I would consider low dose carboplatin (per JCOG 2012 or weekly AUC 2) as chemosensitizer with close monitoring, then consolidation with durvalumab if no progression on CRT and no contra-indication ...
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Answer from: Medical Oncologist at Academic Institution
Carboplatin plus pemetrexed can be considered for non squamous histology. For squamous, taxanes plus platinum is generally preferred, but platinum/etoposide is an alternative listed in the NCCN guidelines.
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Medical Oncologist at Texas Oncology
I am not sure I would give a taxane or cisplatin t...
I am not sure I would give a taxane or cisplatin t...