How do you approach pre-conception counseling in males who are on medications for which there is limited or no data such as Jak inhibitors, apremilast, or belimumab?

I am transparent about the lack of data, but discuss the differences in mechanism of action between cyclophosphamide and thalidomide (the only medications we recommend against conception with a partner) and JAKi, Apremilast, and Benlysta. Prior data has demonstrated a clinically insignificant amount...

Medication issues differ between men with rheumatic disease (RD) who are planning to father a pregnancy and those whose sexual partner is pregnant. Pre-conception concerns for males are two-fold: the potential effect on male fertility, and the potential medication-associated teratogenicity. Men taki...