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How do you approach revaccination after chemotherapy, and what labs (if any) do you use to assess immune reconstitution?

I’m curious how different institutions or providers approach post-chemotherapy revaccination, especially in pediatric patients. I’d love to hear: 1. Do you follow a standard revaccination schedule (e.g., 6 months post-chemo), or tailor it based on labs or clinical factors? 2. Do you routinely check labs prior to revaccination? If so, which ones? • A. Lymphocyte subsets (CD3, CD4, CD8, CD19, NK) • B. Quantitative immunoglobulins • C. Antibody titers (e.g., tetanus, Hib, pneumococcus) • D. Other • E. No labs—follow time-based schedule only 3. Do you have a different approach for kids with B-cell depletion from agents like rituximab? blinatumomab?
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Which labs do you check prior to revaccination of a patient post-chemotherapy?

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