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How do you approach rising gastrin and chromogranin levels without radiographic evidence of disease in patients with gastrinoma that has been fully resected?

Specifically, rising levels noted while on somatostatin analogue.
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Yale School of Medicine
Answered on

We see this scenario with some frequency - rising hormone or peptide levels in functional NETs without radiographic evidence of disease. My next step would be to get the new Ga68 DOTA TATE PET/CT - essentially a new generation octreoscan with high sensitivity and specificity. These scans often pick ...

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