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How do you approach systemic treatment for endometrial endometrioid adenocarcinoma with neuroendocrine differentiation?

In what situations would you use a neuroendocrine chemotherapy regimen over carboplatin+paclitaxel?
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How do you approach systemic treatment for endometrial endometrioid adenocarcinoma with neuroendocrine differentiation?

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2 Answers
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Mednet Member
Gynecologic Oncology · ProMedica
Answered on · Updated on

We treat these as endometrioid primary as the histologic diagnosis states, "endometrioid endometrial adenocarcinoma with neuroendocrine differentiation" instead of "primary neuroendocrine carcinoma of the uterus." Therefore, follow the literature from GOG 209 to support carboplatin/paclitaxel, espec...

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Mednet Member
Mednet Member
Gynecologic Oncology · Covenant Health
Answered on
Carbo or cis plus etoposide
Standard for NE tumors

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