How do you approach the management of resected Stage IIA adenocarcinoma of the colon in an elderly but highly functional patient?
What factors dictate choice of observation versus 6 months of adjuvant peri-operative chemoradiation plus chemotherapy especially if patient did not receive any pre-operative therapy?
Answer from: Medical Oncologist at Academic Institution
Assuming this is a properly staged patient with at least 12 lymph nodes examined, the scenario is a dilemma that many oncologists have faced in their clinics. The survival benefit of adjuvant chemotherapy for stage II colon cancer is small and thus consideration of competing cause mortality and toxi...