How do you approach the treatment of cervical cancer with brain metastases, including leptomeningeal disease, in a patient who has previously experienced grade 4 hematologic toxicity to primary cytotoxic chemotherapy?

What systemic therapy would you consider for treatment of cervical cancer with brain metastases in a patient who has previously experienced grade 4 hematologic toxicity to primary cytotoxic chemotherapy?

• PD-1 / PD-L1 inhibitor
• Tisotumab vedodin-tftv
• Bevacizumab
• Platinum-based chemotherapy
• Other cytotoxic chemotherapy
• Other targeted therapy
• No systemic therapy
• Other