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How do you approach the treatment of Crohn's colitis in the setting of immunosuppression for liver transplant?

1 Answer
Mednet MemberInvited Expert
Gastroenterology · Mayo Clinic
Answered on

Good question, as additional immune suppression can increase the risk of infection. The anti-rejection drug mycophenolate can cause diarrhea, which could mimic a Crohn’s flare.

I individualize Crohn’s therapy in a liver transplant patient. What type of Crohn’s do they have? What meds were they on prior to the transplant? Do they tolerate thiopurines such that something like azathioprine could be used for both anti-rejection and Crohn's? My transplant colleagues are fine with most therapies used ...

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