How do you approach therapy for a patient with stage IIIA NSGCT who received 4 cycles of EP followed by RPLND which revealed residual mixed teratoma and embryonal carcinoma?

Topics: Genitourinary Cancers • Pediatric Oncology • Medical Oncology • Testicular Cancer • AYA

Given persistent embryonal histology on RPLND, do you favor observation or TIP/VIP? What do you use to guide your decision?

Answer from: Medical Oncologist at Academic Institution

This is a query that can never be answered by evidence based medicine. Instead, all we have is (very old) historical data and perhaps common sense and logic. In 1974, we initiated our phase II study of PVB, with 4 courses of induction chemo followed by 2 years of maintenance vinblastine. That was ou...

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Medical Oncologist at Uniformed Services University of the Health Sciences (USUHS)
Thank you very much, Dr. @Lawrence H. Einhorn. If ...

Medical Oncologist at Indiana Univ Simon Cancer Center
If there was serologic progression within 4 weeks ...

Medical Oncologist at Uniformed Services University of the Health Sciences (USUHS)
Thank you for your expertise! Much appreciated, Dr...

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