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How do you approach treatment for patients with proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) with end-stage renal disease who are considering kidney transplant?

Most patients with PGNMID have no detectable disease in their marrow or blood and urine protein cannot adequately be monitored.
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Winship Cancer Institute of Emory University
Answered on

Monoclonal gammopathy of renal significance includes a variety of renal pathologies:

  1. MIDD (LCDD, LHCDD, HCDD).
  2. Monoclonal immunotactoid glomerulonephritis or type 1 cryoglobulinemic glomerulonephritis.
  3. Light chain proximal tubulopathy or crystal-storing histiocytosis.
  4. C3 glomerulopathy with monoclon...

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