How do you approach treatment of vasculitis in a sickle cell disease patient?

There are multiple difficulties that could be seen: steroids can precipitate a sickle cell crisis, vasculitis and sickle cell can produce similar clinical symptoms, our rheumatic medications may cause bone marrow suppression.

1 Answer

Mednet MemberInvited Expert

Rheumatology · Birmingham VA Medical Center

Answered on

Will highly depend on the vasculitis type and the acuity of the situation. For ANCA vasculitis, approaches based on rituximab and low glucocorticoid doses might be attractive (granted not severe disease, e.g. RPGN, DAH which should require pulse glucocorticoids).

For large vessel vasculitis, a si...

Join for free or sign in to see the full answer