How do you balance diagnostic stewardship and high value cost-conscious care when working up a patient with newly diagnosed HIV/AIDS admitted to the ICU with shortness of breath who most likely has PJP pneumonia or cryptococcal infection but is at risk of multiple other pathogens? 

This is an excellent question, which is very based on the patient's clinical presentation as well as the resources you have available to you in your setting, particularly how long it takes for test results to come back. One aspect that should be considered in patients with advanced HIV is that they ...

Multiple concurrent OIs are common in individuals with advanced HIV and contribute significantly to morbidity. Because several infections can emerge simultaneously in the setting of profound immunosuppression, recognizing the likelihood of multiple coexisting pathogens is critical. Early identificat...