How do you choose among SSRIs and dosing strategies for the management of behavioral and psychological symptoms of dementia?

The best supported SSRI for BPSD generally is citalopram. Much of this came out of the CitAD trials [1]. This primarily showed citalopram may be useful for hyperactive behaviors, irritation, but also for depression and anxiety [1, 2]. The effect and response to citalopram, though, may be affected by characteristics such as the severity of BPSD and cognitive baseline [3]. Comparisons of various SSRIs have continued to show the best data for citalopram for BPSD, though somewhat limited [4]. The ma...