In patients with osteoporosis at high fracture risk, what factors most influence your decision to prescribe teriparatide versus abaloparatide?

• Both abaloparatide and teriparatide are very effective anabolic agents to reduce vertebral and nonvertebral fracture risk in patients with osteoporosis (although clinical trials did not demonstrate reduction of hip fracture risk). The two agents are more similar than different and both induce an an...

In the real world, the main reason why I choose one over the other is often dictated by insurance coverage. However, if I have a choice, there are some advantages for abaloparatide over teriparatide.

Both molecules are analogs of parathyroid hormone. Teriparatide is recombinant PTH(1-34), while abal...

Agree with Dr. @Dr. First Last. Although neither company could claim a reduction in hip fractures, there were fewer (1 vs 4) in the teriparatide phase 3 study. Not enough events to make a claim of statistical difference, and therefore no specific hip indication. Large national databases (including a...