How do you choose between initiating long-term therapy with mTOR inhibitors versus opting for interventional treatments such as embolization or surgery in a patient with tuberous sclerosis, experiencing flank pain, and with renal angiomyolipomas larger than 4 cm?

Answer from: at Academic Institution

I have very limited experience, but mTOR has been a game changer for my (2) TS patients. Why would you wait for bleeding, pain, and embolization if you can prevent it?

Answer from: at Academic Institution

This will be a useful article:Effectiveness and safety of everolimus treatment in patients with tuberous sclerosis complex in real-world clinical practiceI have a young patient with TS, and her rAML >4 cm has been stable ever since starting everolimus.

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How do you choose between initiating long-term therapy with mTOR inhibitors versus opting for interventional treatments such as embolization or surgery in a patient with tuberous sclerosis, experiencing flank pain, and with renal angiomyolipomas larger than 4 cm?

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