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How do you compensate for treatment breaks >1 week in patients with NSCLC on concurrent chemoradiation?

Do you use BID treatments toward the end? Do you add additional daily treatments to exceed the prescription dose? Would you alter systemic therapy dose or scheduling?
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How do you compensate for treatment breaks >1 week in patients with NSCLC on concurrent chemoradiation?

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2 Answers
Mednet Member
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Radiation Oncology · Montefiore Einstein Comprehensive Cancer Center
Answered on

Classical radiobiology dictates that some sort of treatment intensification could be indicated for a locally advanced NSCLC patient whose chemoradiotherapy course is interrupted. Though many of my patients have treatment interruptions for a variety of reasons, I almost never increase the total presc...

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Mednet Member
Mednet Member
Radiation Oncology · Physician Health Partners
Answered on

No treatment break is preferred, without escalating the total dose.

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