This is an interesting question. There is some heterogeneity between cooperative groups in their recommendations for pre-sacral nodal coverage. For example, while the RTOG and the UK guidelines recommend coverage of the pre-sacral lymph node basins. The recent Indian POP-RT trial also included ...

I follow the recent NRG Pelvic Lymph Node Consensus Atlas update: 1. Contour the pre-sacral/prevertebral nodes down to the inferior border of S3, with anterior limit generally around 1.5 cm anterior to bone (although there is significant discrepancy for this ranging from 1 cm to 3 cm).2. Contou...