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Topics:
Breast Cancer
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Medical Oncology
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NCI-CCC Tumor Board Question
•
Moffitt Cancer Center
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HR+
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NCI-CCC Breast Tumor Board Question
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Breast Cancer, Non-metastatic
How do you council patients diagnosed with hormone receptor-positive breast cancer currently or interested in taking exogenous hormones (e.g. testosterone) for gender-affirming treatment?
Related Questions
How do you approach initial treatment of unresectable, locally advanced ER+, HER2-negative male breast cancer?
Is there evidence for development of more severe autoimmune toxicities for young patients vs older patients on immune checkpoint inhibitors?
In which situations do you consider post-mastectomy radiation therapy when the patient has a localized node-positive breast cancer with a complete nodal response and minimal residual disease in the breast post-neoadjuvant chemotherapy?
How do you manage adjuvant endocrine therapy for microinvasive HR-positive disease measuring >=1mm in extension?
In light of SABCS 2022, will you use BCI to guide OFS recommendation in the adjuvant setting?
Would you recommend axillary lymph node dissection in a pre-menopausal woman with ER+ PR+ HER2- IDC, s/p lumpectomy and SLN with pT1c pN1 cM0 disease, where 2 sentinel nodes are positive for macrometastasis and 1 SN is positive for micrometastasis?
In which situations do you offer ovarian suppression with chemotherapy to prevent the development of premature menopause in premenopausal women with ER negative breast cancer?
What adjuvant treatment approach would you choose for a premenopausal woman with lymph node positive poorly differentiated metaplastic breast cancer that is ER low+, PR+, HER2 negative?
Would you treat beyond 10 years of adjuvant hormonal therapy for premenopausal woman with high risk ER+ HER2 negative breast cancer who remain premenopausal at the end of 10 year adjuvant hormonal therapy?
What is your cut off on ER percent positivity to treat them as functional triple negative cancer?