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Neurology • Neuro-immunology
How do you counsel B cell-depleted multiple sclerosis patients on the benefits of regular COVID-19 vaccinations?
In light of immunogenicity data of three-dose COVID-19 vaccines (Shawe-Taylor et al., PMID 41425831).
Answer from: at Community Practice
The fact that B cell-depleted patients render a blunted antibody response is not unexpected, but antibodies do not protect from viral infections - cells do. To measure a proper vaccine response, one wants to test T cells from patients to see if they are able to kill viral infected cells. This is wha...
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