How do you counsel patients on the benefits of immunotherapy for anti-MAG neuropathy?

Not a simple issue.

True anti-MAG neuropathy is typically indolent, primarily distal sensory. No treatment has been identified for the neuropathy alone, although there have been and continue to be some treatments in development. So the treatment for anti-MAG neuropathy rests on the treatment of the IgM kappa paraprotein. Sometimes the hematologic issues predominate, with very high IgM levels and evidence of Waldenstrom's or other potentially aggressive lymphoma. But if IgM levels are not that hi...