How do you counsel your breast-cancer survivors about weight-loss/dietary modifications?
Normal body mass index (BMI) and maintenance of weight is associated with a more favorable outcome (in many series both cancer-related and non-related) compared to higher BMI. Similarly higher level of exercise and metabolic equivalent (MET) is also associated with better outcome in many observation...
The data is compelling that excess adipose tissue is bad for outcomes based on metabolic dysfunction, excess hormones, and excess inflammation. I generally counsel patients based on the dozens of randomized studies that exist for weight loss in patients without cancer. There overwhelmingly show that...
All of the above! Minimizing inflammation is so important. I would also add that I tell my patients with (early stage) breast ca about the benefits of time-restricted eating (a.k.a. therapeutic or intermittent fasting). I was very encouraged by the study published in JAMA Oncology in 2016 in which n...