How do you decide between second-line immunotherapy for multifocal motor neuropathy?

E.g., cyclophosphamide, rituximab

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What is your preferred second-line therapy for multifocal motor neuropathy if IVIG is unsuccessful?

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1 Answer

Mednet MemberInvited Expert

Neurology · University of Minnesota

Answered on

There is no FDA-approved second-line immunotherapy for MMN, and there is no single drug with established efficacy from a randomized placebo-controlled clinical trial. In the 1990s and 2000s, there were a couple of case reports indicating efficacy of cyclophosphamide (Pestronk et al., PMID 7969954, B...

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