How do you decide between treating with neoadjuvant nivolumab/ipilimumab versus neoadjuvant pembrolizumab for patients with resectable, clinical node + Stage III melanoma given the NADINA trial results?
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Following the NADINA trial data, what is your preferred treatment approach for patients with resectable stage III melanoma without BRAF mutation?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · University Hospitals
Answered on
The NADINA trial (NCT04949113) has clearly established that the neoadjuvant approach affords a better EFS in patients with clinical stage III melanoma. However, there is no direct comparison between anti-PD1 monotherapy and dual checkpoint inhibition in the neoadjuvant setting. I do not think that s...
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