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How do you decide between using ropeginterferon alfa-2b and peginterferon alfa-2a in MPN?

If a patient is unable to tolerate peginterferon, is there any reason to think they may do better with ropeginterferon?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Hematology · Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital
Answered on

In general, I favor ropeginterferon as it is FDA-approved and allows for less frequent, every 2-week dosing as compared to peginterferon which is used off-label and requires weekly dosing. However, ropeginterferon is not currently approved for ET and in patients where I decide to use interferon in t...

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