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How do you decide who to rechallenge clozapine after it was discontinued for a neutropenic episode?

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Mednet Member
Mednet Member
Psychiatry · Siu Psychiatry

The clozapine rechallenge of the patient previously treated with clozapine but having it discontinued due to clozapine induced neutropenia or absolute neutropenia now has a sizable evidence-based literature suggesting that it can be done safely and successfully. Selecting patients with previous disc...

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Mednet Member
Mednet Member
Psychiatry · Martha E. Crotts, MD, LLC

This isn’t a direct answer to the question as to who to rechallenge. It is related to it, though, in terms of tips on promoting neutrophilia when using clozapine or rechallenging with it. I treat teens and young adults who are neurologically and psychiatrically complex due to prenatal exposure to su...

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