How do you define impaired distal fusion in patients with ICAD?

Yes, the perfusion deficit tends to change over time and is less likely to be as severe in the subacute phase compared to the acute phase.

Once they're out of the acute phase, I define it clinically, i.e., are they having symptoms, and if so are they triggered (low BP, etc) or untriggered? It's helpful to have a baseline perfusion study for future comparison in case they become symptomatic and you want to triage whether off-label hyper...