How do you determine the need to biopsy subcutaneous nodules in infants to rule out Infantile myofibromatosis?

For most subcutaneous nodules in infants of unknown etiology, I would check an ultrasound with doppler first as deep infantile hemangioma and other vascular lesions may be on your differential. If it is not vascular, and small and stable in size, it may be OK to clinically monitor. One may also cons...