How do you determine when to discontinue anti-complement therapy in patients with geographic atrophy who already have center-involving disease given the minimal likelihood of central vision improvement but the potential for more rapid scotoma expansion if treatment is withdrawn?

Answer from: at Community Practice

I will determine the rate of progression prior to starting therapy, and I will monitor for a change in this slope/rate after treatment. If I do not see a change in slope, I will discuss with the patient. In such a situation where the benefit is not apparent, patients will usually choose discontinuat...

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How do you determine when to discontinue anti-complement therapy in patients with geographic atrophy who already have center-involving disease given the minimal likelihood of central vision improvement but the potential for more rapid scotoma expansion if treatment is withdrawn?

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