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How do you determine which patients with ICAS are the best candidates for balloon angioplasty versus those who should continue with aggressive medical management alone?

In light of a recent publication by Sun et al., PMID 39235816 on the BASIS trial for balloon angioplasty for ICAS.
2 Answers
Mednet Member
Mednet MemberInvited Expert
Neurology · Vanderbilt University Medical Center
Answered on

A recent study on JAMA network found angioplasty superior to medical therapy (dual antiplatelet and statin), whereas previous studies have found angioplasty combined with stenting more risky. I am not sure that appropriate guidelines have yet been developed, but I would think that the stenosis must ...

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Mednet Member
Mednet Member
Neurology · University of Colorado, Climate & Health Dept
Answered on

I think there is still inadequate evidence to routinely recommend angioplasty over medical management for symptomatic ICAD. I reserve it for:

  1. Patients in extremis (severe symptoms with CTP suggesting flow failure as the mechanism of injury compared to baseline CTP). I usually obtain a baseline CTP i...

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