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How do you differentiate motor neuron disease from limb girdle muscular dystrophy on electrodiagnostic testing?

What other workup/clinical examination findings do you look for?
1 Answer
Mednet Member
Mednet Member
Neurology · Barrow Neurological Institute
Answered on

I would primarily differentiate these diseases based on history and clinical examination. Motor neuron disease looks like a neuropathic disease, and you are looking for that mix of upper and lower motor neuron signs (hyperreflexia paradoxically found with fasciculations and atrophy). This evolves ov...

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