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How do you do a levodopa trial in the outpatient setting?

In which intervals do you increase the dose and what is the maximum dose you usually try (before considering levodopa to be ineffective in the particular patient)?
2 Answers
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Neurology · The George Washington University
Answered on

In a patient with Parkinsonism whom I am starting levodopa treatment for, I begin by conducting a detailed motor examination using the MDS-UPDRS III to assess baseline symptoms. Typically, bradykinesia and rigidity respond most consistently and robustly to treatment. While tremor and gait disturbanc...

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Mednet Member
Neurology · Buffalo VA Medical Center
Answered on

In my opinion, it is important to consider the phenomenology and the symptomatology of the patient, and how early of the disease we are dealing with. If the patient cognitively is good I do not think we need to be too conservative to start with once a day, one could begin carbidopa or levodopa three...

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