How do you dose FOLFOX when given with concurrent chemoradiation in esophageal adenocarcinoma?
Would you only give three cycles with radiation, or are you adding two more cycles of FOLFOX afterwards?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · Henry Ford Cancer Institute (HFCI)
Answered on
I don’t use FOLFOX within this setting.
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Mednet MemberInvited Expert
Medical Oncology · Memorial Sloan Kettering Cancer Center
Answered on
Continuous infusional 5FU 300 mg/m2 x 96 hours (M-F) weekly for duration of RT, with oxaliplatin 85 mg/m2 q2 weeks (every other Monday) x 3 doses. Of course, you can substitute capecitabine instead of infusional 5FU
[I typically give 2 cycles of induction FOLFOX followed by repeat PET, prior to decid...
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