HomeQuestion
How do you dose FOLFOX when given with concurrent chemoradiation in esophageal adenocarcinoma?
2 Answers
Mednet Member
Medical Oncology · Henry Ford Cancer Institute (HFCI)
I don’t use FOLFOX within this setting.
Mednet Member
Medical Oncology · Memorial Sloan Kettering Cancer Center
Continuous infusional 5FU 300 mg/m2 x 96 hours (M-F) weekly for duration of RT, with oxaliplatin 85 mg/m2 q2 weeks (every other Monday) x 3 doses. Of course, you can substitute capecitabine instead of infusional 5FU
[I typically give 2 cycles of induction FOLFOX followed by repeat PET, prior to decid...